Estudo do sono em portadores de asma difícil controle

Abstract

Among the asthma patients, there are those who do not respond to treatment and are characterized as difficult to control. The Difficult-to-Control Asthma (DCA) affects about 5% of asthmatic patients, and the occurrence of nocturnal symptoms is associated with increased morbidity and inadequate asthma control, and has a major negative impact on quality of life. Therefore, a sleep study in DCA patients is necessary. Objective: To study the sleep of DCA patients and correlate the variables from baseline nocturnal polysomnography. Materials and methods: This study is a cross-sectional study with consecutive sampling. We evaluated 21 subjects (46.4 ± 13.6 years) of both sexes (15 women) diagnosed with DCA, screened at the Santa Casa de Misericórdia de São Paulo s Pulmonary Outpatient Clinic for treatment of DCA. Results: Sleep efficiency observed an average of 72.9% (15.9), which demonstrates that patients slept reasonably approximate the appropriate time that is 85%. The distribution of sleep time between sleep stages showed a slight predominance of NREM 85.5% compared to REM 14.5% . We measured the oxygen saturation in NREM sleep (93.8%) and the minimum REM sleep (83.0%). In relation to micro-arousals, we observed a high value (83.2). When analyzing Epworth scale we found 0-8 (42.85%) 9-12 (14.38%); 13-16 (9.52%) and>16 (33.34%). There were many correlations between polysomnographic variables. Conclusion: Thus, we conclude that asthmatic patients have changes that are difficult to control during sleep and therefore may have comorbidities that further undermine the control of asthma.