Propriedades de medida do teste de degrau incremental modificado para uso em pacientes com bronquiectasia

Abstract

Background: The modified incremental step test (MIST) has been used to assess exercise capacity in chronic lung diseases, but the MIST has not yet been validated in patients with bronchiectasis (BQC). Aim: To investigate the clinimetric properties of TDIM for use in patients with BQC. Methods: Patients diagnosed with BQC responded to the modified Medical Research Council scale (MRCm), underwent spirometry, TDIM and CPET with measurement of expired gases and used for analysis of reproducibility. The TDIM with the highest number of steps (NS) was considered for the validation analysis. Results: The MIST was reproducible, with an intraclass correlation coefficient (ICC [95% confidence interval]) for a NS of 0.93 (0.84-0.96), VO2 of 0.94 (0.90-0.967) . For an analysis of agreement, or standard error according to (SEM) it was 7.6 steps. The minimum detectable difference (DMD) was 21.1 steps. For competition, a moderate correlation was found for VO2 between the best MIST and CPET (r = 0.67 and p <0.001) and a high correlation for HR (r = 0.77 and p <0.001). To validate the validation of a high correlation for the NS found in the MIST and the load in watts obtained in the CPET (r = 0.72 and p <0.001). Desaturation was greater for MIST compared to CPET. Conclusion: The MIST proved to be a reproducible and valid test to assess the functional capacity of patients with BQC.