Estudo da variabilidade da frequência cardíaca em portadores de asma

Abstract

Asthma is a chronic inflammatory disease characterized by hyperresponsiveness of the lower airways, spontaneously reversible or by drugs, some authors relate a possible autonomic control dysfunction with its pathogeneses, but because of the few evidence found the autonomic mechanism in asthma is poorly understood. The aim of the present study was to compare the cardiac autonomic activity in patients with asthma with health individuals. Method: Twenty two individuals with asthma (29 years old) and ten healthy individuals served as control group (28 years old) were studied. All the pacients made a spirometry; test and the HRV was analyzed in the time domain (TD) and the frequency domain (FD). Heart rate and electrocardiographic R-R intervals (iR-R) were recorded for 360 seconds in the supine and seated positions. Results: In TD, the asthma group (AG) presented significantly higher values for the RMSSD and the SDNN in the seated position, in comparison with the control group (CG). In FD, the AG presented significantly higher values for HF components, in the supine position, and for LF components and HF in the seated position. Conclusion: we can conclude that patients with asthma reduced HRV present when compared with healthy individual, because our result showed that they have a reduction in sympathetic and vagal activity.