Eficácia da fotobiomodulação na alopecia X em cães Spitz Alemão: uma série de casos

Abstract

Alopecia X, a dermatopathy of unknown etiology that mainly affects dogs of the breed German Spitz is currently classified as non-inflammatory alopecia. Several treatments with varying success rates, including application of hormonal analogues, low- trauma microneedling and melatonin supplementation have been proposed recently. Photobiomodulation, a therapeutic modality employed in human androgenetic alopecia and alopecia areata, remains unexplored in canine alopecia X. Seven German Spitz dogs of both sexes with alopecia X were enrolled in this study and submitted to photobiomodulation (diode laser, 660nm, power 100mw, with 3 J/point, 4 points per area, 2 sessions/week for 13 weeks, total of 26 sessions). We verified varying degrees of reduction in areas of clinical alopecia, mainly in the right lateral region when comparing T0 x T3 (p= 0.03243). There was an increase in the percentages of hair coverage at dermoscopy at different times (T0, T1, T2 and T3) when individually comparing the anatomical sites [right pelvic limb (p=0.001), left pelvic limb (p=0.005) and right dorsolateral (p=0.012)]; right and left antimeres; and anatomical regions. The results demonstrate the efficacy of photobiomodulation as a treatment modality for alopecia X in German Spitz dogs.