Efeito da fotobiomodulação vascular comparada à fotobiomodulação local no fluxo salivar em indivíduos com xerostomia medicamentosa: ensaio clínico controlado cross-over

Abstract

Saliva is directly related to oral health and homeostasis, and therefore, the occurrence of cavities, periodontitis, fungal and bacterial infections can affect and compromise the population's quality of life. Changes in salivary parameters, such as decreased flow, changes in pH and composition, can lead to changes in oral health, and prevention and treatment strategies need to be studied and developed. Studies using photobiomodulation have shown promise in improving some salivary parameters. The aim of this study is to compare the effect of photobiomodulation with infrared laser (FBML) and red laser (FBMV) protocols on the salivary parameters of adults affected by drug-induced xerostomia. The sample consisted of 12 adults, with healthy teeth, between 29 and 58 years of age, who had saliva collected, the volume measured and the salivary flow determined (ml/min). Resting total saliva was collected before, immediately after photobiomodulation, 30 minutes after and 7 days after the interventions. For FBML (infrared), applications occurred in the regions of the parotid glands bilaterally, as well as in the region of the submandibular and sublingual glands intra- and extraorally and in the wrist for irradiation of the radial artery for the FBMV group (red). After analysis, a statistically significant difference between salivary flow at all times, within groups, was observed. The significance level was set at <0.005. It was concluded that FBM is effective in increasing salivary flow in patients with medical xerostomia in local application or vascular application protocols.